Comparative Clinical Study of Drug-coating Balloon Strategy and Drug-eluting Stent Strategy

Inclusion Criteria: 1. At least 18 years old; 2. Evidence of myocardial ischemia and indications of PCI, stable or unstable angina pectoris, or old myocardial infarction; 3. Primary and bifurcated coronary artery lesions (Medina classification 1,1,1 or 1,0,1 or 0,1,1); 4. Visual angiography of the main branch reference vessel diameter ≥2.5mm, and ≤4.0mm;Branch reference vessel diameter ≥2.0mm; 5. Diameter stenosis of main and branch lesions ≥ 70%, and diameter stenosis of branch lesions ≥ 50%; 6. Visual examination of residual stenosis of main branch lesions after pre-dilation ≤ 30% without vascular dissection or dissection with NHLBI classification A, B, C type. 7. If 2 bifurcation lesions meet the inclusion requirements, only 1 lesion can be included in the study, and the other lesion can be treated or not treated as a non-target lesion. Exclusion Criteria: 1. Main branch or branching target lesions require treatment with more than one device (DES or DCB); 2. There is more than 1 non-target lesion requiring intervention on the target blood vessel; 3. The distance between non-target lesion and target lesion is less than 10 mm; 4. Main and branch lesions \> 26 mm or branch lesions length BBB\> mm; 5. Left main lesion and its bifurcation lesion; 6. Intra-stent restenosis or severe calcification; 7. ST-segment elevation or non-ST-segment elevation myocardial infarction 7 days before surgery; 8. Severe heart failure (NYHA-IV or left ventricular ejection fraction \<35%); 9. Cardiogenic shock; 10. known to have renal failure (EGFR \<30ml/min/1.73m2); 11. Pregnant or lactating women, or women of reproductive age who had family planning or were unable to take adequate contraceptive measures during the study period; 12. Any known allergic reactions or contraindications to the drug and coating or scaffold metal required for DCB in the study; 13. Other DES or DCB treatment contraindications; 14. Failing to sign an informed consent or having an expected life of less than 12 months; 15. Other researchers consider it inappropriate to participate in this study.