Effectiveness of Different Membrane Applications in Vertical Ridge Augmentation

Urban Regeneration Institute30 enrolled

Overview

This randomized clinical trial (RCT) study investigates if there is any difference in absolute vertical bone gain between perforated dense-polytetrafluroethylene (d-PTFE) mesh vs perforated d-PTFE mesh covered with a native collagen membrane. The primary endpoint is absolute vertical bone gain. The secondary endpoints are regeneration rate, complications rate, and pseudoperiosteum formation.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

SINGLE

Enrollment

Conditions

Bone Regeneration Dental Implants Polytetrafluoroethylene

Interventions

Guided bone regeneration with a PTFE membranePROCEDURE

Xenograft bovine spongious bone substitute mixed with autogenous intraorally harvested particulated bone is used and spatially contained with a PTFE membrane secured with Ti pins and screws.

Guided bone regeneration with a PTFE+collagen membranePROCEDURE

Xenograft bovine spongious bone substitute mixed with autogenous intraorally harvested particulated bone is used and spatially contained with a PTFE membrane secured with Ti pins and screws and covered with a Collagen membrane subsequently.

Eligibility

Sex: ALLMin age: 18 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: 1. Partially edentulous patients requiring vertical and horizontal ridge augmentation 2. patients agrees with conditions of the study and sign consent Exclusion Criteria: * Insufficient oral hygiene * Smoking * Alcohol or Drug abuse * acute local or systemic infections * uncontrolled diabetes or other metabolic disease * severe hepatic or renal disfunction * autoimmune disease * radiotherapy in the last 5 years * patients receiving immunosuppressive therapy

Locations (1)

Urban Regeneration Institute

Budapest, Hungary

Outcomes

Primary Outcomes

Complication rate

intrasurgical complications such as flap perforation, mesh exposure, postoperative infection, neurosensory disturbance,

Time frame: 9 months

Bone gain

Vertical and horizontal bone gain measured

Time frame: 9 months

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.