Transcranial Doppler is performed daily in Intensive Care Unit in brain damaged patients. For a few years now, the measurement of the photomotor reflex by quantitative Pupillometry has been routinely performed in Intensive Care Units. The objective of this work is to see if Transcranial Doppler recorded parameters and Pupillary parameters are correlated to the neurological prognosis evaluated at 9 months by the Modified Rankin Score (mRS) and the Glasgow Outcome Scale Extended (GOS-E).
Study Type
OBSERVATIONAL
Enrollment
73
This device measures Mean Systolic Velocity (VMS), Tele-Diastolic Velocity (TDV) and Pulsatility Index (PI),
This device measures the photomotor reflex (basic pupil diameter, percentage of variation, latent and slope of the standard photomotor reflex)
CHU Saint-Etienne
Saint-Etienne, France
Modified Rankin Score (mRS) (0-5)
Modified Rankin Score (mRS) measures the degree of disability following a stroke in a patient (level 0 for patients with no symptoms to level 5 for patients with major disability and total dependency)..
Time frame: Year: 1
Glasgow Outcome Scale Extended (GOS-E) (1-8)
Glasgow Outcome Scale Extended (GOS-E) measure the impact of brain injured (minimum at 1 (Dead) and maximum at 8 (Upper Good Recovery).
Time frame: Year: 1
Mean Systolic Velocity (VMS)
Measured by Transcranial Doppler right and left.
Time frame: At inclusion
Intra-Cranial Pressure (ICP)
Collect on medical file.
Time frame: At inclusion
Pulsatility Index (PI)
Measured by Transcranial Doppler right and left.
Time frame: At inclusion
Tele-Diastolic Velocity (TDV)
Measured by Transcranial Doppler right and left.
Time frame: At inclusion
Basic pupil diameter
Measured by Pupillometry right and left
Time frame: At inclusion
Percentage of variation of the pupil diameter
Measured by Pupillometry right and left
Time frame: At inclusion
Latent and slope of the standard photomotor reflex
Measured by Pupillometry right and left
Time frame: At inclusion
Tissue Partial Oxygen Pressure (PtiO2)
Collect on medical file.
Time frame: At inclusion
Bispectral Index (BIS)
Collect on medical file. BIS is a reflection of the depth of hypnosis
Time frame: At inclusion
Richmond Agitation-Sedation Scale (RASS)
Richmond Agitation-Sedation Scale (RASS) is a symmetrical rating, with positive values for agitation and negative values for the level of consciousness around a point 0 corresponding to a calm and awake patient. Collect on medical file.
Time frame: At inclusion
Heart rate
Collect on medical file.
Time frame: At inclusion
Blood pressure
Collect on medical file.
Time frame: At inclusion
Natremia (mmol/l)
Collect on medical file.
Time frame: At inclusion
Glycemia (mmol/l)
Collect on medical file.
Time frame: At inclusion
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