This is a Phase 2, open-label, randomized controlled trial to determine the effects of Telacebec (Q203) on inhibition of leukotriene production, clinical change, pharmacokinetics, and safety in participants with moderate COVID-19 disease
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
1
Telacebec 100 mg tablet
The Standard of Care treatment and administration thereof will be determined by the Investigator
Chris Hani Baragwanath Academic Hospital
Soweto, Gauteng, South Africa
KwaPhila Health Solutions
Durban, Kwa-Zula Natal, South Africa
TASK Eden
George, Western Cape, South Africa
Biomarker change
Percentage Inhibition of whole blood Leukotriene B4 (LTB4) production at 4 hours post dose SoC versus SoC plus telacebec
Time frame: Day 1 and 14
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