Participants with periodontitis and presence of bilateral intrabony defect will be randomised to have one side of the mouth undergo root surface debridement using hand instruments and ultrasonic scaler alone, while the contralateral side will receive the same treatment, with the addition of the Er:YAG laser. Outcomes studies will be periodontal clinical parameters at 3 months, 6 months, 9 months and 12 months after treatment, radiographic parameters at 12 months, patient-reported parameters and laboratory analyses.
The study is a Double-masked randomised controlled trial with split-mouth design. Participants with periodontitis will be randomised to have one side of the mouth undergo root surface debridement using hand instruments and ultrasonic scaler alone, while the contralateral side will receive the same treatment, with the addition of the Er:YAG laser. Outcomes studies will be periodontal clinical parameters at 3 months, 6 months, 9 months and 12 months after treatment, radiographic parameters at 12 months, patient-reported parameters and laboratory analyses.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Enrollment
28
The WaterLase iPlus tissue cutting system is a unique device with diverse, hard- and soft-tissue dental applications. It utilizes advanced laser and water atomization technologies to safely and effectively cut, shave, contour, roughen, etch, and resect oral hard-tissue, and direct laser energy to perform oral soft-tissue removal, incision, excision, ablation and coagulation.
root surface debridement under local anaesthesia
Pocket resolution
Number of sites with absence of PPD \>5mm following adjunctive laser treatment with RSD (= no need for surgery)
Time frame: 12 months
Gain bone height
Radiographic improvement in bone levels
Time frame: 12 months
Patient-related outcomes
Questionnaire-based patient-reported outcomes
Time frame: 12 months
GCF biomarkers
Change in GCF concentration Biomarkers
Time frame: 12 months
Recession
Changes in gingival recession measurement
Time frame: 12 months
CAL
Changes in clinical attachment level
Time frame: 12 months
Mobility
Changes in mobility scores
Time frame: 12 months
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