The study will examine the effects of eight weeks of equine assisted activities (EAA) on co-regulation, basal physiological values, and symptom severity in veterans with post-traumatic stress disorder (PTSD). Heart rate, respiration rate, surface electromyography (EMG) and plasma concentrations of cortisol, epinephrine, norepinephrine, and oxytocin will be measured at rest and during dyadic interaction tasks (human to human or human to horse) to assess effects of EAA on these measures. Additionally, standard and regularly used questionnaires will be used to monitor PTSD symptom severity during the study and 6-month follow-up period. EAA is expected to lower PTSD symptom severity, and mitigate other physiological changes associated with PTSD.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
NONE
Enrollment
9
Participants interact with the horse and learn how to safely handle the horse.
Rutgers Equine Science Center
New Brunswick, New Jersey, United States
Change from Baseline to the Conclusion of 8 weeks of EAA in PTSD Symptoms as Assessed by PCL-5 & Brief Symptom Inventory
The Brief Symptom Inventory and PTSD Checklist for DSM-5 are questionnaires used to assess the presence and severity of post-traumatic stress disorder symptoms.
Time frame: Symptoms will be assessed prior to the intervention and immediately following the eight week intervention.
Change from Baseline to 2-months After the Conclusion of EAA in PTSD Symptoms as Assessed by PCL-5 & Brief Symptom Inventory
The Brief Symptom Inventory and PTSD Checklist for DSM-5 are questionnaires used to assess the presence and severity of post-traumatic stress disorder symptoms.
Time frame: Symptoms will be assessed prior to the intervention and 2-months after the end of the EAA sessions.
Change from Baseline to 6-months After the Conclusion of EAA in PTSD Symptoms as Assessed by PCL-5 & Brief Symptom Inventory
The Brief Symptom Inventory and PTSD Checklist for DSM-5 are questionnaires used to assess the presence and severity of post-traumatic stress disorder symptoms.
Time frame: Symptoms will be assessed prior to the intervention and 6-months after the end of the EAA sessions.
Co-regulation of heart rate between horse and human during EAA sessions.
Co-regulation will be assessed through the telemetric measurement and modeling of heart rate.
Time frame: Co-regulation of heart rate between horse and human will be assessed once a week during a 30 min session for 8 weeks..
Co-regulation of cortisol between horse and human during EAA sessions.
Co-regulation will be assessed through collection of serial blood samples and subsequent measurement and modeling of plasma cortisol.
Time frame: Co-regulation of cortisol between horse and human will be assessed once a week during a 30 min session in weeks 1,4, and 8 of an 8 week period.
Co-regulation of oxytocin between horse and human during EAA sessions.
Co-regulation will be assessed through collection of serial blood samples and subsequent measurement and modeling of plasma oxytocin.
Time frame: Co-regulation of oxytocin between horse and human will be assessed once a week during a 30 min session in weeks 1,4, and 8 of an 8 week period.
Co-regulation of epinephrine between horse and human during EAA sessions.
Co-regulation will be assessed through collection of serial blood samples and subsequent measurement and modeling of plasma epinephrine.
Time frame: Co-regulation of epinephrine between horse and human will be assessed once a week during a 30 min session in weeks 1,4, and 8 of an 8 week period.
Co-regulation of norepinephrine between horse and human during EAA sessions.
Co-regulation will be assessed through collection of serial blood samples and subsequent measurement and modeling of plasma norepinephrine.
Time frame: Co-regulation of norepinephrine between horse and human will be assessed once a week during a 30 min session in weeks 1,4, and 8 of an 8 week period.
Co-regulation of muscle activity between horse and human during EAA sessions.
Co-regulation will be assessed through collection of surface electromyography (sEMG) from the masseter, brachiocephalas, and cervical trapezius muscles and subsequent modeling.
Time frame: Co-regulation of muscle activity between horse and human will be assessed once a week during a 30 min session over an 8 week period.
Changes in co-regulation of heart rate during dyadic (human-human) interactions following 8 weeks of EAA
Co-regulation will be assessed through the measurement and modeling of heart rate during gazing, not looking, resting, and mimicking tasks.
Time frame: Co-regulation will be assessed prior to the intervention and immediately following the eight week intervention.
Changes in social motor synchrony during dyadic (human-human) interactions following 8 weeks of EAA
Social motor synchrony will be assessed through the measurement and modeling of gross motor movement during a pendulum swinging task.
Time frame: Social motor synchrony will be assessed prior to the intervention and immediately following the eight week intervention.
Changes in resting heart rate following 8 weeks of EAA
Telemetric heart rate monitors will be used to collect resting heart rate.
Time frame: Resting heart rate will be assessed prior to the intervention and immediately following the eight week intervention.
Changes in basal plasma cortisol concentration following 8 weeks of EAA
Plasma concentrations of cortisol will be measured via immunoassay following blood draws during rest.
Time frame: Cortisol concentrations will be assessed prior to the intervention and immediately following the eight week intervention.
Changes in plasma basal oxytocin concentration following 8 weeks of EAA
Plasma concentrations of oxytocin will be measured via immunoassay following blood draws during rest.
Time frame: Plasma oxytocin concentrations will be assessed prior to the intervention and immediately following the eight week intervention.
Changes in basal plasma epinephrine concentration following 8 weeks of EAA
Plasma concentrations of epinephrine will be measured via immunoassay following blood draws during rest.
Time frame: Plasma epinephrine concentrations will be assessed prior to the intervention and immediately following the eight week intervention.
Changes in basal plasma norepinephrine concentration following 8 weeks of EAA
Plasma concentrations of norepinephrine will be measured via immunoassay following blood draws during rest.
Time frame: Plasma norepinephrine concentrations will be assessed prior to the intervention and immediately following the eight week intervention.
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.