MR Fingerprinting for Vestibular Schwannomas

N/AUnknownNCT04851925

Medical University of Vienna50 enrolled

Overview

MR Fingerprinting (MRF) will be performed in patients who will be treated with Gamma Knife radio surgery for a vestibular schwannoma before the intervention. Fifty patients will be included with a vestibular schwannoma of minimum 1cm in size. During follow-up, response of the tumor to radiosurgery will be evaluated for each patient with MRI. The aim of the study is to find patterns of vestibular schwannomas in MRF data which correlate with the type of response to radio surgery, i.e. tumor control after radiosurgery, further tumor growth despite radiosurgery, cystic transformation after radiosurgery.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Vestibular Schwannoma

Interventions

MR FingerprintingOTHER

Specific Magnetic Resonance Imaging protocol

Eligibility

Sex: ALLMin age: 18 YearsMax age: 90 Years

Medical Language ↔ Plain English

Inclusion Criteria: Planned Gamma Knife radiosurgery for vestibular schwannoma of minimum 1cm in size - Exclusion Criteria: Vestibular Schwannoma of less than 1cm in size. Other a priori treatment than Gamma Knife radiosurgery \-

Locations (1)

Medical University of Vienna

Vienna, Austria

RECRUITING

Outcomes

Primary Outcomes

Tumor control

Number of patients without further growth of the tumor on follow-up MRI after radiosurgery

Time frame: 3 years

Tumor growth

Number of patients with growth of the tumor on follow-up MRI after radiosurgery

Time frame: 3 years

Cystic transformation

Number of patients with cystic transformation of the tumor on follow-up MRI after radiosurgery

Time frame: 3 years

Central Contacts

Dorian Hirschmann, MD

CONTACT

+4314040025780 dorian.hirschmann@meduniwien.ac.at

Josa Frischer, MD

CONTACT

+4314040045500 josa.frischer@meduniwien.ac.at

Data from ClinicalTrials.gov

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