To determine whether the use of anti-adhesion barrier after thyroid surgery can prevent the voice changes after surgery, using objective voice-related indicators.
* Randomized controlled study * Including 40 patients in each arm * Treatment: anti-adhesion barrier apply on the thyroidectomy space * Control: No use of anti-adhesion barrier * Primary outcome: VHI-30 (Voice handicap index) * Secondary outcome: findings from stroboscopy, CSL (Computerize Speech Lab) * Outcome measurement: preoperative, post-operative 3 months, post-operative 9 months.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Enrollment
80
Collagen derived anti-adhesion barrier
Inha University Hospital
Incheon, South Korea
RECRUITINGVoice Handicap Index - 30 (VHI-30)
Overall score of VHI (Total 30 points)
Time frame: Preoperative 1 day
Voice Handicap Index - 30 (VHI-30)
Overall score of VHI (Total 30 points)
Time frame: Postoperative 3 months
Voice Handicap Index - 30 (VHI-30)
Overall score of VHI (Total 30 points)
Time frame: Postoperative 9 months
Voice range profile (VRP)
Mininum Hz, Maximal Hz
Time frame: Preoperative 1 day, Post-operative 3 months, Post-operative 9 months.
GRBAS score
Grade, Rough, Breathy, Asthenic, Strained score. (0-3 points in each parameter)
Time frame: Preoperative 1 day, Post-operative 3 months, Post-operative 9 months.
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