Evaluation of Blood Volume Analysis- Guided Management of Decompensated Heart Failure

Inclusion Criteria: 1. Age \> 18 years. In accordance with the Inclusion Across the Lifespan policy, Children will be excluded from the proposed study. ADHF is a condition that rarely affects children and Daxor's BVA-100 lack the reference norms for pediatric use. 2. Admission to the hospital with a primary diagnosis of ADHF. 3. Able and willing to provide informed written consent. Exclusion Criteria: 1. Evidence of acute coronary syndrome or myocardial infarction during qualifying ADHF hospitalization. 2. Evidence of hypertensive crisis or acute valvular regurgitation. 3. The following has occurred within the last 3 months or is planned within the following 3 months: 1. Revascularization procedure. 2. Placement on cardiac transplantation list. 3. Other major cardiac surgery or other surgery. 4. Planned intermittent or continuous intravenous positive inotropic therapy. 5. Severe chronic kidney disease (eGFR\<15 ml/min). 6. Psycho-social factors that interfere with ability to adhere to study procedures (severe dementia, active substance abuse, poorly controlled psychiatric illnesses). 7. Pregnant women or nursing mothers. 8. Women of childbearing potential not using adequate birth control methods. 9. Known hypersensitivity to iodine or eggs. 10. Participation in another heart failure investigational treatment protocol currently or \<30 days prior to enrollment. 11. Evidence of active bleeding or active hemolysis. 12. Hemoglobin measured below 7 g/dl or hematocrit measured below 21%. 13. Patient has received a heart transplant and/or currently treated with mechanical circulatory support. 14. Patients implanted with invasive hemodynamic monitors (i.e. CardioMEMS).