This work is embedded in the context of auditory-motor coupling, which entails the engagement of two systems; the interaction between the music (or repetitive auditory stimuli) and a walking individual (repetitive movements of footfall). In previous studies, the investigators have shown that synchronising steps to beats in music have shown to be feasible in persons with multiple sclerosis, showing increase of step frequency and reduced perceived fatigue\[1, 2\]. In this current work, The investigators expand previous findings with a pilot intervention study, to investigate if synchronisation is necessary to improve cognitive and motor functions. The proposed experiment includes 30 participants, randomised to three arms of a pilot intervention (10 participants per arm). With the intention of a further case-study analysis, the inestigators request to include 4 additional participants (2 PwMS with cognitive impairment, and 2 persons with cerebellar lesion) to only follow the intervention arm 1.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
5
Walking with music than one can synch to
Walking with music than one cannot synch to
Walking without music
Noorderhart Revalidatie & MS centrum
Overpelt, Belgium
12- item multiple sclerosis walking scale
The Multiple Sclerosis Walking Scale is a self-assessment scale which measures the impact of MS on walking. It consists of 12 questions concerning the limitations to walking due to MS during the past 2 weeks. Each item can be answered with 5 options, with 1 meaning no limitation and 5 extreme limitation.
Time frame: Baseline
12- item multiple sclerosis walking scale
The Multiple Sclerosis Walking Scale is a self-assessment scale which measures the impact of MS on walking. It consists of 12 questions concerning the limitations to walking due to MS during the past 2 weeks. Each item can be answered with 5 options, with 1 meaning no limitation and 5 extreme limitation.
Time frame: week 5
6 minutes walking test to calculate the distance walking Index
impact of MS on walking
Time frame: Baseline
6 minutes walking test to calculate the distance walking Index
impact of MS on walking
Time frame: week 5
12 minute walking with sensors
gait dynamics and pattern - detrended fluctuation analysis and spatio-temporal parameters
Time frame: Baseline
12 minute walking with sensors
gait dynamics and pattern - detrended fluctuation analysis and spatio-temporal parameters
Time frame: week 5
Paced auditory serial addition test and symbol digit modality test
to measure cognitive functioning and cognitive fatigability
Time frame: Baseline
Paced auditory serial addition test and symbol digit modality test
to measure cognitive functioning and cognitive fatigability
Time frame: week 5
Motricity Index of dorsi flexors, knee extensors and hip flexors
Muscle weakness
Time frame: Baseline
Motricity Index of dorsi flexors, knee extensors and hip flexors
Muscle weakness
Time frame: week 5
Modified Aschowrth scale Hamstrings, Tricepts Surae, Quadricepts
Spasticity
Time frame: Baseline
Modified Aschowrth scale Hamstrings, Tricepts Surae, Quadricepts
Spasticity
Time frame: week 5
Scale for the assessment and rating of ataxia
Ataxia
Time frame: Baseline
Scale for the assessment and rating of ataxia
Ataxia
Time frame: week 5
Dynamic gait index
Dynamic balance
Time frame: Baseline
Dynamic gait index
Dynamic balance
Time frame: week 5
Time up and Go test
balance
Time frame: Baseline
Time up and Go test
balance
Time frame: week 5
Modified fatigue impact scale
self-reported outcomes for fatigue
Time frame: Baseline
Modified fatigue impact scale
self-reported outcomes for fatigue
Time frame: week 5
Barcelona music reward questionnaire
experience of music reward
Time frame: Baseline
Barcelona music reward questionnaire
experience of music reward
Time frame: week 5
Hospital anxiety and depression questionnaire
anxiety and depression
Time frame: Baseline
Hospital anxiety and depression questionnaire
anxiety and depression
Time frame: week 5
Activities-specific balance confidence scale
self-reported outcome for activity and balance
Time frame: Baseline
Activities-specific balance confidence scale
self-reported outcome for activity and balance
Time frame: week 5
Stroke rehabilitation motivation scale
self-reported motivation questionnaire
Time frame: Baseline
Stroke rehabilitation motivation scale
self-reported motivation questionnaire
Time frame: week 5
the Brunnel Music Rating Inventory-2
self-reported music rating inventory
Time frame: Baseline
the Brunnel Music Rating Inventory-2
self-reported music rating inventory
Time frame: week 5
credibility and expectations questionnaire
self-reporting of credibility of the intervention.
Time frame: week 5
Pre and Post training sessions, 2x a week, 20 minutes for 4 weeks
Before and after each training session * Perceived cognitive and physical fatigue rated on a visual analogue scale * Perceived motivation rated on a Likert scale
Time frame: up to week 4
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