Implementation of GLA:D Program in West Virginians With Osteoarthritis of the Knee

Marshall University24 enrolled

Overview

This study will examine feasibility of implementing Good Life with Osteoarthritis in Denmark (GLA:D) program in West Virginians with osteoarthritis of the knee

Using West Virginia (WV) as an implementation site, this study will examine the feasibility of process implementation and effectiveness of the Good Life with Osteoarthritis in Denmark (GLA:D) program in individuals with osteoarthritis of the knee (KOA). Specifically, the study will examine the feasibility and acceptability of the GLA:D program in individuals with KOA. This study will also assess the magnitude of changes in self-reported knee pain and functional impairments as well as physical performance in individuals who receive GLA:D compared to those who receive control interventions consisting of disease-specific education and exercises for KOA.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

SINGLE

Enrollment

Conditions

Osteoarthritis, Knee

Interventions

GLA:D program (Good Life with osteoArthritis in Denmark)OTHER

GLA:D includes disease-specific education combined with neuromuscular exercises. Control interventions include disease-specific education combined with exercises to optimize movement and strength of the affected knee.

Eligibility

Sex: ALLMin age: 45 YearsMax age: 90 Years

Medical Language ↔ Plain English

Inclusion Criteria: 1. Between 45 to 90 years of age, 2. Osteoarthritis of the knee (KOA) (Kellgren and Lawrence grade 2, 3, or 4) confirmed by an orthopedic surgeon based on plain film radiographs and symptoms, and 3. Recommendation by an orthopedic surgeon to pursue conservative management of KOA. Exclusion Criteria: 1. Prior joint replacement surgery in the ipsilateral knee, 2. Known history of cognitive impairments or any neurodegenerative disease, 3. Any other neurological or musculoskeletal pathologies that have resulted in permanent mobility deficits or functional impairments, 4. Medical conditions that would preclude them from participating in exercise programs, and 5. Inability to read and comprehend English.

Locations (1)

School of Physical Therapy, Marshall University

Huntington, West Virginia, United States

RECRUITING

Outcomes

Primary Outcomes

Change in Knee injury and Osteoarthritis Outcome Score (KOOS4) scores from baseline to 12-weeks later

The KOOS4 is a variant of full length KOOS that has all subscales of full length KOOS (pain, symptoms, ADL, and QOL) except sports and recreation activities subscale. There are 9 items in the pain subscale, 7 items in the symptom subscale, 17 items in the ADL subscale, and 4 items in the QOL subscale. The items across these subscales are scored on the scale of 0 to 4 where 0 indicates no problem and 4 indicates an extreme problem. Each subscale has sufficient stability and dimensionality, and therefore the score for each subscale is calculated independently on 0-100 interval with 0 indicating an extreme problem and 100 indicating no problems.

Time frame: 12-weeks

Central Contacts

Saurabh P Mehta

CONTACT

3046965620 mehtas@marshall.edu

Data from ClinicalTrials.gov

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