Post COVID19 Functional and Cognitive Assessments

Science and Research Centre Koper43 enrolled

Overview

The main objective of the proposed study is to evaluate the impact of coronavirus (2019-nCoV), hereafter COVID -19, on patients' loss of functional capacity after completion of hospital treatment. Specifically, the research will focus on examining changes in musculoskeletal, cardiovascular, and respiratory function, as well as motor control. In addition, we aim to evaluate rehabilitation treatments after recovery from COVID -19 and consider additional preventive measures based on previous experience.

The combination of such a severe respiratory disease as COVID -19 with motor inactivity could have very serious consequences for a person's general health even after COVID -19 symptoms have subsided. To date, the effects of COVID -19 on individual muscle status have not been extensively studied. Therefore, the main objective of this study will be to evaluate the muscle status of patients after COVID -19. In addition, we will be interested in longitudinal monitoring of individuals' rehabilitation, where they will receive instructions based on measured outcomes at hospital discharge. We will also be interested in considering additional preventive measures for future patients based on previous experience of infected and hospitalized COVID -19 patients.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Covid19 Respiratory Disease Walking, Difficulty Cognitive Decline

Eligibility

Sex: ALLMin age: 18 YearsMax age: 100 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Completed hospital treatment after a positive COVID-19 test * Signed written consent Exclusion Criteria: * Still testing positive for COVID -19 at discharge. * Severe musculoskeletal injuries (e.g., disability). * Inability to follow instructions when performing the test.

Outcomes

Primary Outcomes

Timed up and go test (TUG)

Functional performance of the patients from sitting to standing, walking and turning

Time frame: Change in time on TUG between both assessment points (pre- to 2 months post-measurement)

Pulse wave velocity (PWV)

Measuring endothelium function in supine

Time frame: Change in PWV between both assessment points (pre- to 2 months post-measurement)

Spirometry

Measurement of lung function, specifically the forced vital capacity (FVC)

Time frame: Change in FVC (%) between both assessment points (pre- to 2 months post-measurement)

Secondary Outcomes

Walking velocity

measurement of gait velocity on the 4m path.

Time frame: Change in gait velocity between both assessment points (pre- to 2 months post-measurement)

Trail making test B

Measurement of executive control using the TMT B test

Time frame: Change in time to solve the TMT B test between both assessment points (pre- to 2 months post-measurement)