Effect of Interval Training on Arterial Stiffness in Women With Hypertension

Cairo University50 enrolled

Overview

this study is aiming to assess the chronic effect of the interval training program on arterial stiffness in women with hypertension

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

DOUBLE

Enrollment

Conditions

Arterial Stiffness

Interventions

interval training exerciseOTHER

interval training exercise

Eligibility

Sex: FEMALEMin age: 40 YearsMax age: 60 Years

Medical Language ↔ Plain English

Inclusion Criteria: * physically inactive * BMI 30-40 * Stage 1 and 2 hypertension * Elevated BP as systolic BP ≥130 mm Hg and/or diastolic BP ≥85 mm Hg measured at the brachial artery. Exclusion Criteria: * Medications known to affect weight or appetite * Any disease associated with exercise intolerance. * Women were taking hormone replacement therapy

Locations (1)

Faculty of physical therapy

Cairo, Egypt

Outcomes

Primary Outcomes

Central arterial stiffness measurements (Pulse Wave Velocity [PWV], augmentation index )

Pulse wave analysis (PWA) of the women in the two groups: pre and post treatment for pulse wave velocity (PWV) and augmentation index(AIx) Pulse Wave Velocity \[PWV\], augmentation index (AIx @75HR) and resting heart rate were measured using analysis equipment which called Non-invasive blood pressure measurement system using "Mobil-O-Graph 24h PWA " with Hypertension Management Software Client Server (HMS-CS 4.3). PWA was performed using an oscillometric Mobil-O-Graph R 24 h PWA Monitor device (I.E.M GmbH, Germany) with integrated ARCSolver® software

Time frame: two months

Secondary Outcomes

blood lipid profile

blood analysis will be used to measure lipid profile (high and low-density lipoprotein, cholesterol, triglyceride)

Time frame: two months

interleukin 6

blood analysis will be used to measure interleukin 6

Time frame: two months

blood pressure (systolic and diastolic)

resting Blood pressure was monitored from the right arm using an automated digital electronic BP monitor (Omron digital BP monitor, Model 11 EM 403c; Tokyo Japan).

Time frame: two months

Data from ClinicalTrials.gov

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