The recent literature has highlighting the importance of the time of SB and the level of physical activity (PA) as predictors of metabolic cardio risks. Now, sedentary lifestyles are well recognized as one of the causes of mortality. As with physical activity, a dose-response relationship appears to exist: mortality would increase with time spent in sedentary behaviors. However, this relationship would not be linear: the more the daily sitting time increases, the more the consequences on mortality are important. It is now well demonstrated that time spent in sedentary adult behaviour finds primarily its origin in the work, characterized by prolonged and uninterrupted periods of sitting. Many strategies have been settled to break the prolonged sitting time. The most promising one seem to be the use of active workstations (standing, walking, cycling, stepping) because they reduce sedentary time at work and increase physical activity with positive effects on the global health. However inter variability in energy response have been identified during a sit to stand allocation with subject "savers" profile showing an increase in energy expenditure while others categorized as "non-savers" increased significantly their energy expenditure between sitting and standing position. As others active workstation strategies exist, this study aim to first, better characterize energy response to posture and activity allocation (15min sit-15min stand-15min sit-15min low intensity cycling), secondly to identify parameters that could explain different energy profile.
Subject will have an inclusion visit during a medical consultation where the eligibility criteria to participate to this study will be checked. During a second experimental visit, subjects will have to take a calibrated breakfast. Three hours after the breakfast, body composition will be assessed and energy expenditure and substrates oxidation will be measured with an indirect calorimetry device during 15min in a sitting position fallowed by 15min in standing position , 15min in a sitting position and 15min of low intensity cycling with a cycling desk. Then subjects will underwent physical capacity test : * 6min step test * Handgrip test * lower limb strength test Finally, subjects will be equipped with accelerometer and inclinometer device they will need to wore during 7 days.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
PREVENTION
Masking
NONE
Enrollment
50
15min sitting, 15min standing, 15min sitting, 15 min low intensity cycling
CHU de Clermont-Ferrand
Clermont-Ferrand, France
energy expenditure
Using an indirect calorimetry device change in energy expenditure will be assed during the 1h posture /activity allocation (15min sitting, 15min standing, 15min sitting, 15 min low intensity cycling)
Time frame: change from baseline to the experimental visit (Day 1)
physical activity level (ActiGraph)
using acceleometry device (ActiGraph Gt3x)
Time frame: during the 7 days following the experimental session
physical activity level (ActivPAL)
using accelerometry (ActivPAL)
Time frame: during the 7 days following the experimental session
Body composition : fat mass and fat free mass
body composition will be assessed by bioelectrical impedance device (TANITA MC-780MA)
Time frame: day 0
upper limb strength
will be assessed with handgrip for upper limb muscle
Time frame: during the experimental session after energy expenditure assessment (Day 1)
aerobic fitness
will be assessed with the Step Test 6 minutes
Time frame: during the experimental session after energy expenditure assessment (day 1)
lower limb strength
will be assessed with isokinetic dynamometer
Time frame: during the experimental session after energy expenditure assessment (day1)
eating profile with DEBQ questionnaire (Dutch Eating Behavior Questionnaire)
the questionnaire will identify with a scale (items to rank between never and always) three major factors influencing eating behavior "emotional , restrained and external eating". For all items score goes from 0 to 5pts and the lower score the better/healthier.
Time frame: during the experimental session before energy expenditure assessment (day 1)
eating profile with TFEQ questionnaire (Three-Factor Eating Questionnaire)
the questionnaire will identify with a scale (items to rank between never and always) three major eating profiles (cognitive restraint, disinhibition, hunger). For Items 1 to 16 score goes from 4 to 1pts, from items 17-21 score goes from 1 to 4 pts. Global score is calculated the lower the healthier.
Time frame: during the experimental session before energy expenditure assessment (day 1)
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.