Vaso-occlusive crisis in Sickle cell disease might alter myocardial function through micro vascular obstruction. Evaluation of strain alteration using speckle tracking echocardiography is a non invasive technique that may allow us to observe such myocardial dysfunction. No such study has yet been conducted in patient hospitalised in intensive care unit. Our hypothesis is that strain alteration during vaso-occlusive crisis, if they do exist, can be correlated with other markers of myocardial injury such as troponin level or thoracic pain.
Study Type
OBSERVATIONAL
Enrollment
30
There are no particular intervention performed in patients in this study, because echocardiography is part of the standard of care of patients hospitalised in the ICU for vaso occlusive crisis.
Medical Intensive Care Unit
Le Kremlin-Bicêtre, France
RECRUITINGGlobal longitudinal strain
Measure of global longitudinal strain using speckle tracking echocardiography
Time frame: Day 0
Global longitudinal strain
Measure of global longitudinal strain using speckle tracking echocardiography
Time frame: Day 1
Global longitudinal strain
Measure of global longitudinal strain using speckle tracking echocardiography
Time frame: Day 2
Troponine level
Time frame: Day 0
Troponine level
Time frame: Day 1
Troponine level
Time frame: Day 2
Electrocardiogram QT interval
Time frame: Day 0
Electrocardiogram QT interval
Time frame: Day 2
Electrocardiogram ST elevation
Time frame: Day 0
Electrocardiogram ST elevation
Time frame: Day 2
Electrocardiogram negative T waves
Time frame: Day 0
Electrocardiogram negative T waves
Time frame: Day 2
Thoracic pain
Numerical rating scale from 0 to 10 assessed by the patient
Time frame: Day 0
Thoracic pain
Numerical rating scale from 0 to 10 assessed by the patient
Time frame: Day 1
Thoracic pain
Numerical rating scale from 0 to 10 assessed by the patient
Time frame: Day 2
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