P5 is planned as a prospective observational study, collecting evidence-based perioperative data on patient history and demographics, physical function, cognitive measures, psychological, and biological markers associated with increased pain susceptibility, and psychophysical measures of pain processing. The study will use daily ecologic momentary assessment (EMA) of physical and emotional parameters, and collect data on perioperative events. Follow up will occur 3 months and 6 months postoperatively.
Study Type
OBSERVATIONAL
Enrollment
2,500
Washington University in St Louis
St Louis, Missouri, United States
Persistent Postsurgical Pain (PPSP)
Clinically meaningful PPSP will be defined as pain in the surgical area present 3 months after surgery which fulfils one of the following criteria: 1) pain intensity on rest or movement ≥3 on 0-10 numerical rating scale (NRS), or 2) pain interference with any of the seven Brief Pain Inventory items (general activity, mood, walking ability, normal work \[including housework\], relations with other people, sleep, and enjoyment of life) ≥3 on 0-10 scale.
Time frame: up to 7 months following consent
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