Evaluate the safety, pharmacokinetics and efficacy of HEC89736 in patients with Relapsed or Refractory B-cell Hematologic Malignancies
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
TREATMENT
Masking
NONE
Enrollment
5
HEC89736 tablets QD every 28 days for each cycle
Beijing Cancer Hospital
Beijing, Beijing Municipality, China
Jiangsu Province Hospital
Nanjing, Jiangsu, China
Dose limited toxicities evaluated with NCI-CTC AE v5.0 after the first dose
Incidence of dose limited toxicities and associated dose of HEC89736
Time frame: Dosing started until the 28th day
Adverse events evaluated by NCI CTCAE 5.0
Incidence of adverse events and associated dose of HEC89736
Time frame: From the frst dose to within 30 days after the last dose
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