Cardiovascular Responses in Adolescent Idiopathic Scoliosis Girls

Tung Wah College20 enrolled

Overview

The aims of this pilot study are to determine the metabolic demand and exercise intensity level of E-Fit exercise intervention by evaluating the cardiovascular responses in AIS girls and whether the cardiovascular responses for AIS girls performing E-Fit will behave in the same way as compared to healthy controls. We hypothesise that 1) the metabolic demand and exercise intensity of E-Fit exercise intervention is equivalent to moderate-to-vigorous level; and 2) AIS girls have different cardiovascular responses as compared to healthy controls

AIS girls and age- and gender-matched healthy controls will perform the E-Fit exercise intervention for two trials and gas exchange parameters including oxygen consumption (VO2) and carbon dioxide production (VCO2) will be taken continuously during the exercise. Comparison of VO2 and VCO2 between AIS and healthy controls when performing E-Fit exercise will be made.

Study Type

INTERVENTIONAL

Allocation

NON_RANDOMIZED

Purpose

BASIC_SCIENCE

Masking

NONE

Enrollment

Conditions

Adolescent Idiopathic Scoliosis

Interventions

ExerciseBEHAVIORAL

Two trials of 7-min High Intensity Interval Training (HIIT) with 12 different exercises. Each exercise lasts for 30 seconds continuously with 10 seconds rest interval.

Eligibility

Sex: FEMALEMin age: 10 YearsMax age: 16 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Cobb angle greater or equal to 15 degree * Cleared for physical activity by doctor Exclusion Criteria: * Cobb angle greater or equal to 40 degree, or * Scoliosis with any known etiology, scoliosis with skeletal dysplasia, know endocrine and connective tissue abnormalities, or * Known heart condition or other diseases that could affect the safety of exercise, or * Eating disorders or GI malabsorption disorders, or * Currently taking medication that affects bone or muscle metabolism

Locations (1)

Tung Wah College

Hong Kong, Hong Kong

Outcomes

Primary Outcomes

Respiratory gas measurement

Breath-by-breath measurement of cardiorespiratory and gas exchange parameters to analyse oxygen consumption (VO2 in ml/min) and carbon dioxide production (VCO2 in ml/min).

Time frame: Day 1

Blood Pressure

Blood pressure (mmHg) will be measured using an electronic sphygmomanometer.

Time frame: Day 1

Heart rate

Heart rate (bpm) will be measured using a fingertip oximeter.

Time frame: Day 1

Oximetry

Peripheral capillary oxygen saturation (%) will be measured using a fingertip oximeter.

Time frame: Day 1

Secondary Outcomes

Maturity assessment

Sexual maturity using Tanner Scale and onset of menarche will be measured.

Time frame: Day 1

Modified Baecke Questionnaire

Habitual physical activity level will be assessed by self-administered questionnaire.

Time frame: Day 1

Physical Activity Rating Questionnaire for Children and Youth (PARCY)

Physical activity level and intensity will be assessed by self-administered questionnaire.

Time frame: Day 1

Body height

Body height (cm) will be measured with standard stadiometry techniques.

Time frame: Day 1

Data from ClinicalTrials.gov

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