To investigate the effect of perioperative lidocaine infusion on the neutrophil extracellular trapping after minimally invasive surgery for stomach cancer
To investigate the effect of perioperative lidocaine infusion on the neutrophil extracellular trapping, especially citrullinated histone3, neutrophil elastase, myeloperoxidase
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
SUPPORTIVE_CARE
Masking
QUADRUPLE
The participants receive perioperative lidocaine infusion with general anesthesia for gastrectomy.
The participants receive perioperative normal slaine infusion with general anesthesia for gastrectomy.
Seoul St.Mary's Hospital
Seoul, Seocho-gu, South Korea
serum concentration of NET(neutrophil extracellular trapping)-related biomarker
NET-related biomarker (citrullinated histone3, neutrophil elastase, myeloperoxidase)
Time frame: 24 hours after surgery
quality of recovery
The quality of recovery is assessed using questionnaire. This questionnaire includes 15 items. The score range is from 0 to 150. The higher score means the better quality of recovery after surgery.
Time frame: 24 hours after surgery
postoperative pain
The postoperative pain is assessed using numeric rating scale (NRS; 0=no pain, 10=the maximal pain)
Time frame: 24 hours after surgery
survival of patients
The survival of patients is assessed using electronic medical record.
Time frame: 5 years
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