This study aims to investigate the brain activation during different motor patterns, including motor execution (ME), motor imagery (MI), action observation (AO) and mirror visual feedback (MVF). In addition, the relations between brain activation and motor performance will also be explored. This study includes two parts, which are upper limb and lower limb part. While executing all the tasks, brain activation in primary motor cortex(M1), premotor cortex(PMC), and supplementary motor cortex(SMA) will be monitored by functional near-infrared spectroscopy. One-way ANOVA with repeated measure will be used to detect the differences of brain activation level between each mode. Pearson correlation coefficient will be used to determine the relations of brain activation and motor performance.
In upper limb part, subjects will be instructed to execute functional reaching task in ME, MI, AO, and MVF mode. During ME mode, motor performance including maximum speed, maximum acceleration, and jerk will be collected simultaneously. In the lower limb part, subjects will be instructed to walking over ground in ME, MI, and AO mode. During ME mode, the temporal and spatial gait parameters, including speed, stride time, cadence, and stride length will be collected.
Study Type
OBSERVATIONAL
Enrollment
43
National Taiwan University Hospital
Taipei, Taiwan
Brain activities over primary motor cortex
A multichannel wearable fNIRS imaging system (NIRSport2, NIRx Medical Technologies LLC, Glen Head, NY, USA) is used to detect the hemodynamics.
Time frame: Day 1
Brain activities over premotor cortex
A multichannel wearable fNIRS imaging system (NIRSport2, NIRx Medical Technologies LLC, Glen Head, NY, USA) is used to detect the hemodynamics.
Time frame: Day 1
Brain activities over supplementary motor area
A multichannel wearable fNIRS imaging system (NIRSport2, NIRx Medical Technologies LLC, Glen Head, NY, USA) is used to detect the hemodynamics.
Time frame: Day 1
Motor performance of upper limb -maximum speed
cm/s
Time frame: Day 1
Motor performance of upper limb -maximum acceleration
cm/s\^2
Time frame: Day 1
Motor performance of upper limb - jerk
cm/s\^3
Time frame: Day 1
Motor performance of lower limb - gait speed
cm/s
Time frame: Day 1
Motor performance of lower limb - cadence
steps
Time frame: Day 1
Motor performance of lower limb - stride time
second
Time frame: Day 1
Motor performance of lower limb - stride length
cm
Time frame: Day 1
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