Mangos are a rich source of nutrients such as carotenoids, vitamin C and fiber, as well as polyphenols and phenolic acids such as mangiferin, ellagic acid, and gallotannins. Mango extract has been reported to protect against photo-aging of the skin in an animal model exposed to UVB radiation, reducing the length of wrinkles and increasing collagen bundles. Beta-carotene and other carotenoids are known to provide skin protection from sunlight, but other compounds in mangos, may also be important in reducing oxidative damage in aging skin. We have recently completed a pilot study showing a clear trend in skin wrinkle reduction when postmenopausal women consumed 85g of Ataulfo mangos, four times per week for 16 weeks. To confirm and extend these results, a larger study is proposed.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
70
85g mango, 4x/week
Wrinkles
Wrinkle score measured by Facial Image Analysis System
Time frame: week 20
Facial Hydration
Moisture measured by MoistureMeterSC
Time frame: week 20
Facial Redness
Redness measured by Facial Image Analysis System
Time frame: week 20
Facial Elasticity
measured by Cutometer
Time frame: week 20
Gut microbiome
analyze for changes in gut microbiome diversity measures (Shannon Diversity)
Time frame: week 20
Gut microbiome
Analyze for the relative abundance of short chain fatty acid producing bacteria
Time frame: week 20
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