This pilot study will evaluate the effects of a Springtime Home Cleanse on skin, gut, metabolic, and mental health. The study will also assess changes in overall quality of life. The results will be used to design a larger cleanse-based study in the future.
Short-term dietary cleanses and other popular detoxification methods are thought to eliminate accumulated toxins from the body and subsequently, promote health and well-being. Although previous studies have reported improvements in weight loss, blood pressure and insulin resistance with these practices, there is not enough scientific evidence to corroborate these claims. Therefore, the objective of this pilot study is to determine the effects of a short-term dietary cleanse on various parameters of skin, gut, metabolic and mental health and evaluate the aforementioned health claims.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
TREATMENT
Masking
NONE
Enrollment
18
Subjects will participate in the full 9-day Springtime Home Cleanse, including the week prior to a pre-cleanse transition period. The cleanse includes a transition week, 9 days of a monodiet, internal oleation with ghee, external oleation, herbs, purgation, and an enema. During this time, subjects will also attend daily online meetings on Facebook Live throughout the cleanse and on AyurPrana's AyurLearn online portal to participate in guided mediation and yoga. Subjects will also use these platforms to access daily cleanse instructions and journaling topics.
Integrative Skin Science and Research
Sacramento, California, United States
Microbiota diversity
Evaluation of gut microbiome diversity
Time frame: 3 weeks
Microbiome intestinal markers
Zonulin, calprotectin, antibodies against LPS
Time frame: 3 weeks
Serum hemoglobin A1c (HbA1c) levels
Evaluate serum HbA1c level via ZRT Laboratories Cardiometabolic Panel
Time frame: 3 weeks
Serum high-sensitivity C-reactive protein (hsCRP) level
Evaluate serum hsCRP level via ZRT Laboratories Cardiometabolic Panel
Time frame: 3 weeks
Serum triglyceride (TG) level
Evaluate serum TG level via ZRT Laboratories Cardiometabolic Panel
Time frame: 3 weeks
Serum low density lipoprotein (LDL) level
Evaluate serum LDL level via ZRT Laboratories Cardiometabolic Panel
Time frame: 3 weeks
Serum high density lipoprotein (HDL) level
Evaluate serum HDL level via ZRT Laboratories Cardiometabolic Panel
Time frame: 3 weeks
Serum very low density lipoprotein (VLDL) level
Evaluate serum VLDL level via ZRT Laboratories Cardiometabolic Panel
Time frame: 3 weeks
Salivary diurnal cortisol pattern
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.
Salivary diurnal cortisol pattern via ZRT Laboratories Saliva Hormone Test
Time frame: 3 weeks
Facial redness - image based
BTBP Clarity Mini 3D camera
Time frame: 3 weeks
Facial wrinkles - image based
BTBP Clarity Mini 3D camera
Time frame: 3 weeks
Facial trans-epidermal water loss (TEWL)
Vapometer, Delfin Technologies
Time frame: 3 weeks
Tongue changes - image based
Evaluate changes in tongue coating, discoloration, depressions, indentations, and cracking via iPad imaging
Time frame: 3 weeks
Quality of Life Survey Based Assessment
Self assessment using World Health Organization (WHO) Quality of Life Questionnaire
Time frame: 3 weeks
Safety assessments for GI distress
Self assessment using Digestive Questionnaire
Time frame: 3 weeks
Blood pressure
Time frame: 3 weeks
Heart Rate
Time frame: 3 weeks
Respiratory Rate
Time frame: 3 weeks