The purpose of this study is to accumulate and quantitatively analyze data on the microbiome, serotonin signaling and genetics, and inflammatory cytokines from patients with Autism Spectrum Disorder and Fragile X Syndrome. Computational analysis of multi-dimensional datasets will be used to establish a "Diagnostic and Therapeutic Index" - an objective set of tools that can help differentiate subtypes of Autism Spectrum Disorder and develop more accurate methods of diagnosis and response to treatment.
Study Type
OBSERVATIONAL
Enrollment
300
participants will submit at minimum two of four required samples: fecal, urine, finger/toe-prick blood, and cheek swab, collected at home via commercially available kits
Broward Health Medical Center
Fort Lauderdale, Florida, United States
RECRUITINGmicrobial diversity profile
genetic analysis of microbial species in fecal samples
Time frame: 2 years
differences in serotonin levels
molecular analysis of blood/urine/fecal samples
Time frame: 2 years
differential expression of serotonin-related signaling molecules
genetic analysis of cheek swabs
Time frame: 2 years
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