Objective of the study is to evaluate the effect of Taxifolin Aqua therapy on the indicators of respiratory function, the state of the arterial wall, the contractile function of the myocardium, as well as to assess the effect of Taxifolin Aqua therapy on markers of biological age, quality of patients life.
The study will include 100 patients who had covid pneumonia 3 months ago. If the inclusion / exclusion criteria are met, the patient is asked to sign an informed consent to participate in the study. Consenting patients are randomized to an intervention group or a control group. The control group (n = 50) will receive standard therapy, patients from the intervention group (n = 50) will be prescribed Taxifolin Aqua 30 mg per day in addition to standard therapy. Patients will be randomized to the control and main group using random number spreadsheets, assuming that the control and main groups will be homogeneous in the main demographic and clinical parameters. Patient monitoring will be carried out within 2 months from the date of inclusion. A follow-up visit is scheduled in 2 months. During the study, the patient will be regularly monitored for tolerance and safety of therapy with Taxifolin Aqua.
Study Type
INTERVENTIONAL
Allocation
NON_RANDOMIZED
Purpose
SUPPORTIVE_CARE
Masking
NONE
Enrollment
100
Dietary supplement
Russian Clinical Research Center for Gerontology
Moscow, Russia
Dynamics of spirometry indices
spirometry
Time frame: In 2 months after recruitment
Dynamics of ECHO CG
ECHO CG
Time frame: In 2 months after recruitment
Dynamics of pulse wave velocity
applanation tonometry
Time frame: In 2 months after recruitment
Dynamics of augmentation index
applanation tonometry
Time frame: In 2 months after recruitment
Dynamics of biological age
Laboratory indicators
Time frame: In 2 months after recruitment
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