Postoperative Noninvasive Ventilation After Upper Abdominal Surgery in Chronic Obstructive Lung Disease

South Valley University100 enrolled

Overview

In Qena university hospital a prospective, randomized study was carried out on 100 COPD patients, all were divided into; conventional therapy without NIV (C group) 50 patients or with prophylactic NIV(N group) 50 patients.NIV applied for approximately 30 to 45 min at 2- to 4-h intervals for 48 h following surgery . Primary endpoint was the acute respiratory events (ARE) .Secondary endpoints were acute respiratory failure (ARF), intubation rate, mortality rate, infectious and non-infectious complications, and ICU stay.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

NONE

Enrollment

100

Conditions

Acute Respiratory Failure Post Surgical (Diagnosis)

Interventions

NIVDEVICE

NIV applied for approximately 30 to 45 min at 2- to 4-h intervals for 48 h following surgery

Eligibility

Sex: ALLMin age: 18 YearsMax age: 75 Years

Medical Language ↔ Plain English

1. Inclusion criteria: * Age˃18 years, scheduled for upper abdominal surgery under general anesthesia. * Moderate to very severe COPD (GOLD II to IV). * ASA functional status II or greater. 2. Exclusion criteria: * Contraindications to the application of NIV. * Sleep apnea syndrome. * Facial deformation. * Inability to follow the study.

Locations (1)

asmaa Mostafa

Luxor, Egypt

Outcomes

Primary Outcomes

acute respiratory events

patients %

Time frame: 28days

Secondary Outcomes

acute respiratory failure

patients %

Time frame: 28 days

intubation rate

patients %

Time frame: 28 days

ICU mortality

patients %

Time frame: 28 days

ICU length of stay

days

Time frame: 28 days

infectious and non infectious complications

patients %

Time frame: 28 days

Data from ClinicalTrials.gov

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