The aim is to establish adequate and suitable protocols for PD patients and to determine the WB-EMS effects on muscle strength, balance, walking, cognitive functions,neurotrophic factors and alpha-synuclein. Thirty-six PD patients, aged from 50 to 80 years, will be recruited and randomly assigned to two experimental groups (EGs and EGc) and one control group (CG), in order to perform dynamic movements with WB-EMS. EGs will undergo to 12-20 minutes of progressive supervised WB-EMS (4 sec. 85 HZ and 4 sec. rests) combined to light dynamic movements, two-time per week for 12/24 weeks. EGe will undergo to 12-20 minutes of progressive supervised WB-EMS 7 Hz) combined with cardiovascular training with rowing machine. CG will not perform any type of physical activity. Pre and post intervention assessment will be carried out on the following areas: physical assessment, neurocognitive, neurotrophic factors and alpha-synuclein assesments. A 3 months follow-up will be performed.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
36
Bodyweight exercise training combined with WB-EMS (2 times/week) with a 85Hz electrical impulse
Cardiovascular training , using the rowing machine, combined with WB-EMS (2 times/week) with a 7Hz electrical impulse
No physical activity
Università degli Studi del Molise
Campobasso, Italy
REPETITIONS NUMBER CHANGE
30S ARM CURL TEST
Time frame: 14 Weeks
REPETITIONS NUMBER CHANGE
30S SIT TO STAND TEST;
Time frame: 14 Weeks
TIME(S) CHANGE
SODA POP TEST ;
Time frame: 14 Weeks
TIME(S) CHANGE
8 FEET UP AND GO TEST ;
Time frame: 14 Weeks
DISTANCE (M) CHANGE
6 MINUTE WALKING TEST
Time frame: 14 Weeks
UPPER LIMB STRENGHT CHANGE
HAND GRIP TEST
Time frame: 14 Weeks
LOWER BODY FLEXIBILITY
CHAIR SIT AND REACH TEST
Time frame: 14 Weeks
BALANCE AND STABILITY TEST CHANGE
TINETTI BALANCE AND GAIT EVALUATION TEST
Time frame: 14 Weeks
NUMBER OF ERRORS CHANGE
STROOP TEST;
Time frame: 14 Weeks
NUMBER OF ERRORS CHANGE
REY AUDITORY VERBAL LEARNING TEST
Time frame: 14 Weeks
TIME(S) CHANGE
STROOP TEST
Time frame: 14 Weeks
TIME(S) CHANGE
TRAIL MAKING TEST CHANGE
Time frame: 14 Weeks
NEUROTROPHIC FACTORS CHANGE
BLOOD DRAW
Time frame: 14 Weeks
ALPHA-SYNUCLEIN CHANGE
BLOOD DRAW
Time frame: 14 Weeks
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