Safety and Tolerability of TWP-201 in Healthy Female Subjects

Inclusion Criteria: * Body weight ≥ 45 kg, 19 ≤ body mass index (BMI) ≤ 28 kg /m2; * Women with sexual experience, potential fertility and regular menstrual cycle (25-34 days) (including boundary value); * The levels of sex hormones were normal or abnormal without clinical significance at the time of screening; * The physiological structure of uterus and bilateral ovaries was normal or abnormal by ultrasound examination, without clinical significance; Exclusion Criteria: * Known the history of stage III / IV endometriosis, submucosal myoma and endocrine abnormality within 6 months before enrollment; * Known the history of ovarian hyperstimulation syndrome (OHSS); * Premature ovarian failure, decreased ovarian reserve function (Antral Follicle Counting \< 3), high ovarian response, polycystic ovary syndrome, unexplained vaginal bleeding or endometrial hyperplasia; * Any FSH or HMG preparations were used within 3 months before the first study; * Pregnancy or lactating women.