Pulmonary embolism (PE) is the third leading cause of cardiovascular mortality. The Pulmonary Embolism Response Team (PERT) concept offers a rapid and multidisciplinary approach focused on improving outcomes for patients with PE. All institutionalized PERTs in Poland have been invited to join the study. The goal of this registry is to describe current practice and outcomes in patients with acute PE treated by Polish PERTs.
Pulmonary embolism (PE) is the third leading cause of cardiovascular mortality. The presentation of PE may vary from asymptomatic or mild exertion disturbances (low-risk PE) treated with anticoagulants only to hemodynamic "obstructive" collapse and death (high-risk PE). Patient outcome depends on ability of the right ventricle to sustain the increased afterload caused by the embolic burden. Careful risk stratification is crucial, and the Pulmonary Embolism Response Team (PERT) concept offers a rapid and multidisciplinary approach focused on improving outcomes for patients with PE by advancing its recognition, diagnosis, and treatment. All institutionalized PERTs in Poland have been invited to join the study. The data is administrated by the Poznan University of Medical Sciences on the basis of an agreement between the PERT centres. The goal of this registry is to describe current practice and outcomes in patients with acute PE guided by Polish PERTs. The primary data recorded include details of each patient's clinical status, co-morbidities, the administered treatment modalities, the results of additional studies (ab tests results, ECG, imaging studies), and the outcome. The data collection will have no impact on the way the patient is diagnosed and treated.The study endpoints comprise respiratory failure, shock, death distal systemic embolization (i.e. stroke) and major or minor bleeding complications classified according to the International Society on Thrombosis and Haemostasis classification.
Study Type
OBSERVATIONAL
Enrollment
10,000
Poznan University of Medical Sciences
Poznan, GreaterPoland, Poland
RECRUITINGClinical improvement during hospitalization
Incidence of arterial blood saturation increase \>92%
Time frame: 24 hours after specific PE treatment implementation
Ventricular strain reduction
Rate of right ventricular strain reduction (right ventricle/left ventricle ratio assessment) in echocardiography
Time frame: 24 hours after specific PE treatment implementation
Early mortality rate from pulmonary embolism
Number of patients who died from pulmonary embolism (right heart failure)
Time frame: Two weeks since PE diagnosis
Total mortality rate from pulmonary embolism
Number of patients who died from pulmonary embolism (right heart failure)
Time frame: 3 months since PE diagnosis
Bleeding events incidence
Incidence of major bleedings assessed using ISTH criteria
Time frame: 3 months since PE diagnosis
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