Study of M5049 in Healthy Japanese and Caucasian Participants

Inclusion Criteria: * Japanese participants must be first generation (born in Japan) with both biological parents and all 4 biological grandparents being Japanese native born. Caucasian participants must have both biological parents and 4 biological grandparents of Caucasian descent * Overtly healthy participants as determined by medical evaluation, including medical history, physical examination, laboratory tests, and cardiac monitoring (blood pressure, heart rate and 12-Lead resting ECG) * Participants with body weight within 45 to 90 kilograms (kg) (female) and 55 to 90 kg (male) and body mass index (BMI) between 18.5 and 29.9 kilograms per meter square (kg/m\^2) * A Caucasian participant will be matched by body weight (± 20% body weight \[kg\]), height (± 15% height \[centimeter (cm) \]) and sex to each Japanese participant * Other protocol defined inclusion criteria could apply Exclusion Criteria: * Participants with history of clinically relevant disease of any organ system that may interfere with the objectives of the study or provide a risk to the health of the participant * Participants with history of relevant drug hypersensitivity * Participants with history of splenectomy, epilepsy, other neurological disorders or neuropsychiatric conditions * Participants with history of a tuberculosis and positive Screening test for hepatitis B surface antigen * Participants with history of alcoholism or drug abuse * Other protocol defined exclusion criteria could apply