Iron and Vitamin Supplementation in Hip/Knee Surgery

I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio60 enrolled

Overview

Randomized controlled trial to evaluate the efficacy of oral iron supplementation plus cofactors in reducing the prevalence of preoperative anemia in a cohort of 60 patients undergoing elective prosthetic hip or knee surgery.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

SUPPORTIVE_CARE

Masking

DOUBLE

Enrollment

Conditions

Orthopedic Disorder Hip Arthropathy Knee Arthropathy Anemia Iron Poor Blood

Interventions

Iron plus folic acid, vitamin B2, B6, B12, C, and EDIETARY_SUPPLEMENT

A number of 30 subjects are supplemented with iron plus folic acid, vitamin B2, B6, B12, C, and E daily for 60+/-15 days before orthopedic surgery.

Eligibility

Sex: ALLMin age: 60 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Males and females * ASA 1, 2, or 3 * No neuropsychiatric conditions * Acceptance of informed consent * Elective prosthetic hip or knee surgery Exclusion Criteria: * ASA 4 * Present or past neuropsychiatric conditions * Hip or knee revision surgery * Use of iron as dietary supplement * Known erythrocytosis * Incompatible hypersensitivities * Iron metabolism disorders * Lymphoproliferative disorders

Locations (1)

Istituto Ortopedico Galeazzi

Milan, Italy

Outcomes

Primary Outcomes

Change of blood hemoglobin levels

Change of hemoglobin concentration (g/dl) from baseline and after 60 days +/- 15 days

Time frame: Baseline and 60 days +/- 15 days

Data from ClinicalTrials.gov

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