The Effect of Liposome Vitamin C on the Absorption and Metabolism of the Human Body.

TCI Co., Ltd.11 enrolled

Overview

To evaluate the difference between vitamin C in the form of oral liposomes and general vitamin C in a fixed period of time in plasma and urine.

we recruited 11 healthy subjects and adopted a cross-over test. the subjects need to take 3 tests during trail. After each test was completed, a washout period of 14 days was required before the next test start. The subjects were informed to consume one sachet vitamin C without liposome, liposomal process A vitamin C, or liposomal process B vitamin C (Double Nutri™) every test, and vitamin C concentration was measured at baseline (0 hours), 0.5, 1, 2, 3, 4, and 8 hours after taking test sample.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

DOUBLE

Enrollment

Conditions

Vitamin C Deficiency

Interventions

vitamin C without liposomeDIETARY_SUPPLEMENT

subjects need to take 3 tests during trail. After each test was completed, a washout period of 14 days was required before the next test start

liposomal process A vitamin CDIETARY_SUPPLEMENT

subjects need to take 3 tests during trail. After each test was completed, a washout period of 14 days was required before the next test start

liposomal process B vitamin C (Double Nutri™)DIETARY_SUPPLEMENT

subjects need to take 3 tests during trail. After each test was completed, a washout period of 14 days was required before the next test start

Eligibility

Sex: ALLMin age: 20 YearsMax age: 60 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: 1. Adults between 20-60 years old, 2. No heart, liver, kidney, endocrine and major organic diseases Exclusion Criteria: 1. Renal insufficiency and dialysis 2. Cancer 3. Underweight (BMI≦17) or obese (BMI≧27), 4. Take chronic disease drugs, 5. Blood pressure systolic blood pressure ≧130 mmHg or diastolic blood pressure ≧85 mmHg, 6. Too high fasting blood glucose ≧ 100 mg/dL, 7. Triglyceride ≧ 150 mg/dL,Total cholesterol ≧ 200 mg/dL, 8. Have a history of vitamin C allergy, 9. People with mental illness, 10. Pregnant or breastfeeding women, 11. Hematosis, 12. Kidney stones, 13. Long-term vitamin C supplements (at least 200 mg per day for more than one month)

Locations (1)

Research & Design Center, TCI CO., Ltd

Taipei, Taiwan