Microvascular Changes in OCT-angiography in Type 1 Diabetes Mellitus at the Onset of the Disease and After Optimization of Glycemic Control.

Inclusion Criteria: * Patients with Type 1 Diabetes at diagnosis of the disease (less than 7 days after diagnosis) * Age equal to or greater than 18 years * Signature of the informed consent by the patient / legal guardian. Exclusion Criteria: * Metabolic situation of ketosis or ketoacidosis, according to clinical criteria established in the protocol of the Endocrinology and Nutrition Service. The patient will be a candidate once the ketonemia is absent (value \<1 mmol / L). * Previous diagnosis of dyslipidemia and any previous lipid-lowering treatment * Previous diagnosis of hypertension and any previous hypotensive treatment * Previous diagnosis of any form of cardiovascular disease, including heart failure. * Previous kidney disease, and presence of advanced kidney failure (estimated glomerular filtration rate \<60 ml / min) * Presence of diabetic retinopathy identifiable by conventional eye fundus or retinography, or other concomitant retinal vascular pathology (hypertensive retinopathy, venous occlusion, arterial obstruction, etc.) * History or presence of retinal pathology that may alter its structure and / or the validity of the measurements (retinal detachment, epiretinal membrane, high myopia -understood as an axial length greater than or equal to 26mm measured by "IOL Master" biometry-, neovascular membrane, choroidal tumors, etc.) * History of posterior uveitis or retinal vasculitis * Glaucoma and neuro-ophthalmological pathology that can alter the neuroretinal structures. * Refractive media opacity that prevents a correct acquisition of images and, therefore, their evaluation * Dementia or intellectual disability that prevent proper collaboration when acquiring images