Effects of Oxytocin and Vasopressin on Moral Decision Making

University of Electronic Science and Technology of China180 enrolled

Overview

To determine whether the neuropeptide oxytocin (OXT) and vassopressin (AVP) influence moral decision making

In a double-blind, between- subject placebo (PLC) controlled design, subjects will first complete a series of questionnaires in terms of mood, clinical symptoms, and traits. After that their moral judgment and emotion towards both verbal descriptions of moral dilemma scenarios and pictures of specific interpersonal ones will be assessed and the effect of intranasal OXT and AVP between both male and female healthy subjects will be investigated.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

BASIC_SCIENCE

Masking

DOUBLE

Enrollment

180

Conditions

Healthy

Interventions

OxytocinDRUG

intranasal administration of oxytocin (24 IU)

VasopressinDRUG

intranasal administration of vasopressin (20 IU)

PlaceboDRUG

intranasal administration of placebo

Eligibility

Sex: ALLMin age: 18 YearsMax age: 30 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * healthy subjects without past or current psychiatric or neurological disorders Exclusion Criteria: * pregnancy

Locations (1)

Xiaoxiao Zheng

Sichuan, Sichuan, China

Outcomes

Primary Outcomes

Effect of OXT and AVP on behavioral index of moral decision task

intensity of feelings

Time frame: 45 mins - 105 mins

Data from ClinicalTrials.gov

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