This study aims to map the impact of anodic transcranial direct current stimulation (tDCS) for prolonged home use applied to the primary motor cortex and the left dorsolateral prefrontal córtex (DLPFC), compared to the respective treatments simulated in fibromyalgia.
This study aims to map the impact of anodic tDCS for prolonged home use applied to the primary motor cortex and the left dorsolateral prefrontal córtex (DLPFC), compared to the respective treatments simulated in fibromyalgia, targeting the outcomes of the following axes: (1) pain intensity and functional capacity; (2) psycho cognitive functions; (3) neurophysiological markers; (4) biological rhythm markers; (5) to map the potential of neurophysiological markers, biological rhythm and history of trauma in childhood and adolescence in functional capacity, depressive symptoms and working memory tests.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Enrollment
66
A stimulation device, that releases 2.0mA current by a 35 cm2 electrode direct located on a specific location on the scalp for 20 minutes
Hospital de Clinicas de Porto Alegre
Porto Alegre, Rio Grande do Sul, Brazil
RECRUITINGlevel of pain
response on the Numeric Verbal Scale (NPS) from 0-10 during the conditioning stimulus
Time frame: Up to 60 minutes before and after tDCS stimulation
Psychocognitive functions
episodic memory measured by Rey Verbal test
Time frame: Pre and Pos 20 days Intervention
circadian rhythmicity
urinary 6-sulfatoxymelatonin levels
Time frame: Pre and Pos 20 days Intervention
Effect of tDCS over DLPFC on cognitive function.
Cortical connectivity
Time frame: Pre and Pos 20 days Intervention
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