This research compares the effects of one-year continuous whole egg supplement vs. egg yolk substitutes and control on anthropometry, biochemical blood parameters, metabolic enzymes and microbiome data in primary school children.
This research study determine the long-term effects of egg supplementation on growth, blood lipoproteins, blood proteins, nutritional status, metabolic enzymes and microbiomes in children, enrolling in the school lunch program.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
TRIPLE
Enrollment
635
whole eggs
yolk-free egg substitutes
Faculty of Medicine Siriraj Hospital, Mahidol University
Bangkok Noi, Bangkok, Thailand
changes in body weight following the dietary intervention
weight (kg), weight for age (z-score) analysis
Time frame: week 0 (baseline), week 13 - 14, week 34 - 35
changes in height following the dietary intervention
height (cm), height for age (z-score) analysis
Time frame: week 0 (baseline), week 13 - 14, week 34 - 35
change in blood protein levels following dietary intervention
transferrin (mg/dl), pre-albumin (mg/dl), albumin (g/dl) analysis
Time frame: week 0 (baseline), week 13 - 14, week 34 - 35
changes in blood biochemistries following dietary intervention
fasting blood sugar (mg/dl), cholesterol (mg/dl), triglyceride (mg/dl), HDL-Cholesterol (mg/dl), LDL-Cholesterol (mg/dl)
Time frame: week 0 (baseline), week 13 - 14, week 34 - 35
changes in microbioma and stool metabolites following dietary intervention
bacterial type, fatty acids in stool
Time frame: week 0 (baseline), week 13 - 14, week 34 - 35
changes in blood biochemistries following dietary intervention metabolite enzyme
lecithin-cholesterol acyltransferase (LCAT), cholesterol ester transfer protein (CETP), apolipoprotein C (APOC), apolipoprotein E (APOE)
Time frame: week 0 (baseline), week 13 - 14, week 34 - 35
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