Comparing the Effectiveness of Cyanoacrylate Tissue Adhesives and Conventional Sutures

Melaka Manipal Medical College20 enrolled

Overview

This study compares the effectiveness of two materials used for intraoral wound closure after removal of impacted mandibular third molar tooth. One Group received braided black silk suture and the other group received N-butyl 2-octyl cyanoacrylate tissue adhesives.

Conventional method of wound closure after removal of impacted mandibular molar is by suturing the wound using braided black silk suture and allowing for primary healing. Suturing in the most posterior region of oral cavity is not easy, it requires more time and additional skills as well. Patient has to come for a second visit for removal of suture. Moreover tight sutures may lead to ischemia and necrosis. Tissue adhesives adopts the idea of sutureless wound closure. They are even sloughed off from the surface of mucosa 7 days after the application. This study compares the effectiveness of conventional sutures and tissue adhesives in closure of intraoral surgical wounds after removal of mandibular third molar.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

SINGLE

Enrollment

Conditions

Wound Heal

Interventions

closure of wound using n- butyl 2-octyl cyanoacrylate tissue adhesivePROCEDURE

Application of cyanoacrylate tissue adhesives over the surgical wound

closure of wound using braided silk suturePROCEDURE

suturing the surgical wound using braided black silk

Eligibility

Sex: ALLMin age: 17 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * patients requiring surgical removal of mesioangular, position A impacted mandibular third molar * clean incisions approximately 2-3 cms in length which can be approximated * Healthy (ASAI) or patients with mild systemic disease no functional limitations * Patients not allergic to the drugs or anesthetic agents used in the surgical protocol Exclusion Criteria: * Patients taking any medications that influences wound healing * Patients on non steroidal anti inflammatory drugs * smokers * uncooperative patients patients allergic to cyanoacrylate

Locations (1)

Melaka Manipal Medical College

Melaka Tengah, Melaka, Malaysia