The purpose of this study is to evaluate the effect of ANG-3777 on placebo-corrected change from baseline, QT/corrected QT (QTc) interval, following single intravenous (IV) doses in healthy volunteer adults.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Enrollment
48
Arms assigned to this intervention will receive 2 mg/kg, IV, Fasted
Arms assigned to this intervention will receive 6 mg/kg, IV, Fasted
Arms assigned to this intervention will receive normal saline, IV, Fasted
Quotient Sciences
Miami, Florida, United States
Change from baseline in corrected QT interval by Fridericia's formula for ANG-3777 at the therapeutic and supra-therapeutic dose levels compared to placebo
Time frame: Day 1, Day 5, Day 9 and Day 13
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Arms assigned to this intervention will receive 400 mg, Oral, Fasted