The goal of this study is to develop and test the feasibility of a supportive care model (POISE) for patients with metastatic Non-small Cell Lung Cancer (NSCLC). The main questions are * is POISE feasible to deliver and acceptable to patients * what is the effect of POISE on the distress patients feel related to their uncertain future, their confidence in their ability to manage cancer, and their understanding about what to expect Participants in the randomized controlled trial will receive either the new supportive care model, POISE, which consists of four visits with a trained palliative care clinician, or care as usual, and will be asked to complete three surveys.
This research study involves an intervention consisting of four sessions with palliative care specialists who have been additionally trained to evaluate and address the specific psychosocial issues and health-promoting behaviors of patients with NSCLC. The research study procedures include: * Four 60-minute visits with a trained palliative care clinician * Questionnaires and an exit interview * Chart Review It is expected that about 70 participants currently receiving targeted therapy at Massachusetts General Hospital for lung cancer will take part in this research study: 10 patients in an open pilot study, followed by 60 patients in a randomized controlled trial.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
SUPPORTIVE_CARE
Masking
SINGLE
Enrollment
70
POISE (Patient-centered, Optimal Integration of Survivorship and palliative carE) is a brief, population-specific intervention that consists of four sessions with palliative care specialists who have been additionally trained to evaluate and address the specific psychosocial issues and health-promoting behaviors of patients with long, uncertain cancer trajectories.
Massachusetts General Hospital
Boston, Massachusetts, United States
RECRUITINGFeasibility of POISE - enrollment
≥60% enrollment among eligible patientsamong patients in the POISE group
Time frame: 20 weeks
Feasibility of POISE - completion of all sessions among patients in intervention group
≥70% completion of all sessions in the intervention arm
Time frame: 20 weeks
Feasibility of POISE - completion of surveys in both arms
≥70% completion of all surveys in both arms
Time frame: 20 weeks
Acceptability
4-item measure of satisfaction and comfort with the intervention
Time frame: 20 Weeks
Emotional coping with prognosis and prognostic awareness
Subscale of Prognostic Awareness Impact Scale
Time frame: 12 weeks
Emotional coping with prognosis and prognostic awareness
Subscale of Prognostic Awareness Impact Scale
Time frame: 20 weeks
Self efficacy
Self-Efficacy of Management of Chronic Disease 6-Item Scale asks patients to rate their confidence in managing symptoms and activities related to chronic disease on a 1-10 scale, ranging from 1 (not at all confident) to 10 (totally confident).
Time frame: 12 weeks
Self efficacy
Self-Efficacy of Management of Chronic Disease 6-Item Scale asks patients to rate their confidence in managing symptoms and activities related to chronic disease on a 1-10 scale
Time frame: 20 weeks
Documentation of Goals and Values
The investigators will apply a previously developed natural language processing/machine learning (ML) algorithm to palliative care and oncology notes from the study period in order to identify goals of care conversations using an inductive supervised ML classifier. Notes with a predicted probability of greater than 0.5 will be classified as containing goals of care documentation.
Time frame: 20 weeks
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