Investigators analyze the anesthesia of the endolaryngeal laser surgery in patients with smoking with or without monitoring of depth of anesthesia (bispectral index)
All participants are informed about the investigation and are signed the Informed Consent before anesthesia. The study takes place at the Department of Otorhinolaryngology, University of Pecs, Hungary. Between June 2021 and May 2022 ASA I or II patients aged 18-65 years, scheduled for elective endolaryngeal laser surgery with TCI (target-controlled infusion, propofol). Exclusion criteria are epilepsy, psychiatric illness, cerebrovascular or congenital neuromuscular disease. Participants are randomized to two anesthetic groups, anesthesia with or without bispectral index monitoring.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
OTHER
Masking
SINGLE
Enrollment
50
intraoperative single-channel electroencephalography monitoring of the depth of anesthesia
Department of Anaesthesiology and Intensive Therapy
Pécs, Ifjuság Str.13., Hungary
PTE Department of ENT
Pécs, Hungary
circulation
blood pressure (mmHg)
Time frame: through study completion, an average of 1 year
cardiac function
pulse rate (beats/minute)
Time frame: through study completion, an average of 1 year
oxygenization
oxygen saturation (%)
Time frame: through study completion, an average of 1 year
ventilation
end-tidal carbon-dioxide (mmHg)
Time frame: through study completion, an average of 1 year
depth of anesthesia
bispectral index level (number between 1-100), the target intraoperative level 40-60, lower and higher are worse
Time frame: through study completion, an average of 1 year
cognitive functions
cognitive functions test (Montreal Cognitive Assessment) score (number between 0-30, minimum=0, maximum=30), higher number is better
Time frame: through study completion, an average of 1 year
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