The main objective of this trial is to investigate safety, tolerability and pharmacokinetics (PK) and pharmacodynamics (PD) of BI 1820237 alone or together with a single low dose of liraglutide in male subjects with overweight/obesity (otherwise healthy) following subcutaneous administration of single rising doses.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Enrollment
95
CRS Clinical Research Services Mannheim GmbH
Mannheim, Germany
Percentage of subjects with drug-related adverse events
Time frame: up to 48 days
Area under the concentration-time curve of the analyte in plasma over the time interval from 0 extrapolated to infinity (AUC0-∞)
Time frame: up to 38 days
Maximum measured concentration of the analyte in plasma (Cmax)
Time frame: up to 38 days
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Paracetamol-ratiopharm®