Resistance Training Effects on Gut Microbiome and Cardiometabolic Outcomes

Inclusion Criteria: * Age 18-35 years * BMI: 25-45 kg/m2 * Sedentary lifestyle * Consistent diet patterns * Weight-stable (\<4 kg change over the last 3 mo) * Willingness to adhere to resistance training protocol and not change diet * Non-smoker \>1 year or more Exclusion Criteria: * Disabilities preventing adherence to resistance training protocol * Recent start of medications that affect metabolism or appetite * Antibiotics * Diabetes * Drug therapy for coronary artery disease, peripheral artery disease, congestive heart failure, or dyslipidemia * Uncontrolled hypertension and blood pressure ≥ 180/110 * Gastrointestinal disease and/or bariatric surgery * Smoking * Illicit drug use * Pregnant or lactating individuals