The aim of this study is to investigate the effect of opioid-free anesthesia using dexmedetomidine and lidocaine instead of remifentanil infusion, on the acute postoperative pain after the gynecological laparoscopy
This study is performed to investigate the effect of dexmedetomidine and lidocaine the postopeative pain, shivering, nausea and vomiting after the gynecological laparoscopy.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
SUPPORTIVE_CARE
Masking
TRIPLE
dexmedetomidine iv bolus for 10 minutes followed by the infusion of 0.1-1 ug/kg/h during general anesthesia
remifentanil iv infusion of 0.5-5 ng/ml (effect site concentration using TCI) during general anesthesia
lidocaine iv bolus followed by the infusion of 1.5mg/kg/h during general anesthesia
Seoul St.Mary's Hospital
Seoul, Seocho-gu, South Korea
Seoul St.Mary's Hospital
Seocho, South Korea
postoperative pain in recovery room
The pain level is assessed by using NRS (numeric rating scale; 0=no pain , 10=the worst pain)
Time frame: 30 minuetes after the completion of surgery
shivering in recovery room
The incidence of shivering is assessed by questioning Yes or No.
Time frame: 30 minuetes after the completion of surgery
postoperative nausea and vomiting (PONV)
The incidence of PONV is assessed by questioning Yes or No
Time frame: 30 minutes after the completion of surgery
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