The aim of this study is to evaluate the analgesic efficacy of combined ultrasound (US)-guided pectoral nerve (PECS) block II and transversus thoracic plane (TTP) block versus US-guided serratus anterior plane (SAP) block in female patients undergoing modified radical mastectomy.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Enrollment
70
Patients will receive unilateral US-guided PECS II block and TTP block on the side of the operation after induction of general anesthesia.
Patients will receive US-guided SAP block after induction of general anesthesia.
Faculty of Medicine Tanta University
Tanta, Elgharbia, Egypt
The total amount rescue analgesic consumption (morphine) in the first 24 hours postoperatively.
Rescue analgesia in the form of morphine (3mg IV) will be given if the VAS is ≥ 40, repeated with lock out interval of 5 min guided with the occurrence of complications till the VAS is decreased to less than 40.
Time frame: First 24 hours postoperatively.
The degree of postoperative pain
Postoperative pain will be assessed by Visual Analog scale (VAS) on admission to Post-Anesthesia Care unit (PACU) and at 30 minutes and then 1,2,4,6,12,18 and 24 hours postoperative. VAS (0-100; where 0 represents no pain and 100 represents the worst pain).
Time frame: First 24 hours postoperatively.
Time to first rescue analgesia request.
Rescue analgesia in the form of morphine (3mg IV) will be given if the VAS is ≥ 40, repeated with lock out interval of 5 min guided with the occurrence of complications till the VAS is decreased to less than 40.
Time frame: First 24 hours postoperatively.
Intraoperative fentanyl consumption.
Additional boluses of fentanyl 0.5 µg /kg will be administered in case of inadequate analgesia that defined as increase of heart rate (HR) and /or mean arterial blood pressure (MAP) more than 20 % from baseline
Time frame: Intraoperative
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