Development of an Innovative Health Ingredient From Marine By-products for the Healthy Aging

Inclusion Criteria: * Male or female subjects, aged between 60 and 73 years old (including age limits), * BMI between 20 and 30 kg/m2, * Not diagnosed with Alzheimer's disease and autonomous, * 26 \< MMSE \<= 29, * PAL TEA \> 57, * Affiliated with a social security plan, * Able to understand the study and consent, * Available to come to the 5 visits required for the study, * Informed and have signed an informed consent. Exclusion Criteria: * Person who has participated in the last 3 months or is currently participating in another clinical trial that may interfere with the evaluation of the primary endpoint (memory). * Subject consuming food supplements likely to have an effect on memory or within less than 6 months * Subject consuming high level of Vitamin A and/or Long chain n-3 PUFA evaluated by a food frequency questionnaire * Restrictive or unbalanced diet (hypocaloric, vegetarian, vegan, …) self-declared at V0 * Fish consumption more than twice a week * Allergy to fish * Life threatening pathology (such as cancer) in remission for less than 1 year or still ongoing, * Diabetes (type 1 or type 2), * Cardiovascular disease diagnosed within less that 2 years, with the following exceptions: subjects with controlled (medicated) high blood pressure and/ or controlled (medicated) can be included, * Personal history of stroke * Personal history of schizophrenia or other psychiatric disorders * Ongoing neuroleptic treatment * Current depressive episode characterized at clinical interview according to the criteria of module A of the MINI (Mini International Neuropsychiatric Interview) * Unbalanced thyroid disease (treatment modified in the last 6 months), * For women: hormone replacement therapy started less than 3 months ago or for which the dosage of the treatment has been modified in the last 3 months or whose dosage is likely to be modified during the study * Chronic inflammatory bowel disease or chronic disorders of intestinal absorption * Diagnosed inflammatory bowel disease or chronic intestinal absorption disorders * Current antidepressant treatment or discontinuation within the last 3 months * Substance abuse or alcoholism within the last 6 months (smoking is allowed) * General anesthesia in the last 6 months or scheduled in the next 6 months * Alcohol abuse: more than 2 standard drinks per day, * Subjects with clinical characteristics that may interfere with the performance of the tests (e.g.: acute visual or hearing impairment) * Person placed under court protection, * Person participating in another research study with an exclusion period still in progress ongoing,