the Efficacy and Safety of Etanercept （Yi Sai Pu) in Chinese Patients With Moderate-to-Severe Psoriasis

Inclusion Criteria: 1.18 to 75 years of age 2.Moderate to severe chronic psoriasis, BSA≥3% 3.Duration of psoriasis≥6 months 4.Patients must be candidate for systemic therapy or phototherapy 5.No contradiction to Etanercept 6.Informed consent must be obtained 7.For female, ß-hCG test is negative and contraception is accepted Exclusion Criteria: 1. Diagnosis of pustular psoriasis, erythroderma psoriasis or drug-induced psoriasis 2. Having severe infections, including hepatitis, HIV and tuberculosis 3. No live vaccines 12 weeks before enrollment, through the study and 1 year after the last dose of Etanercept 4. Having significant allergies to biological agents 5. Having the previous experience of biologics 6. Having a history of malignancy 7. Having contradictions to Etanercept 8. Refusal of contraception 9. Having serious or unstable/uncontrolled illnesses