Evaluation of OxxyneaGS in Acute Glycemic Regulation on Light Hyperglycemic Subjects

Fytexia10 enrolled

Overview

This study aims to evaluate and select the best combination of polyphenol and white kidney bean ingredients in the acute glycemic modulation after a complete meal by measuring blood glucose and insulin.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

SUPPORTIVE_CARE

Masking

QUADRUPLE

Enrollment

Conditions

Hyperglycemia, Postprandial

Interventions

Verum T1DIETARY_SUPPLEMENT

Verum T1 is a placebo: microcristalline cellulose. Daily dosage is 1000 mg in 3 capsules.

Verum T2DIETARY_SUPPLEMENT

Verum T2 is a 11500AAIU/g white kidney bean extract. Daily dosage is 1000 mg in 3 capsules.

Verum T3DIETARY_SUPPLEMENT

Verum T3 is a 11500AAIU/g white kidney bean extract. Daily dosage is 565 mg in 3 capsules

Eligibility

Sex: ALLMin age: 20 YearsMax age: 50 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Glycemia: 100-125mg/dL * Both sexes * Overweight BMI range (27-32) * Age: 20-50 years old Exclusion Criteria: * Metabolic/Chronical disease * Menopausal women * Being pregnant, breastfeeding or wanting to have a baby * Former obese with a history of yoyo effect * Have been involved in a weight loss program in the past 12 months or subjected to weight reduction surgery * Having started or quit smoking, having a high alcohol consumption * Have in the past been in a long-term antibiotherapy (1 month or more) and/or a regular antibiotherapy in the past 12 months * Allergy to olive, artichoke, black currant, grapefruit, grape, white kidney bean, olive, pomegranate.

Locations (1)

UCAM

Murcia, Spain

Outcomes

Primary Outcomes

Acute change in glycemia in response to a meal, by measuring glucose concentration in the blood at different time points

Time frame: 8 hours

Secondary Outcomes

Lipid profile evolution after a meal

Time frame: 8 hours

Oxxidative stress variation after a meal, measured by oxidized/reduced glutathione (GSH/GSSG)

Time frame: 8 hours

Acute change in insulinemia in response to a meal, by measuring insulin concentration in the blood at different time points

Time frame: 8 hours

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.

Verum T4 is a 17500AAIU/g white kidney bean extract. Daily dosage is 1000 mg in 3 capsules

Verum T5DIETARY_SUPPLEMENT

Verum T5 is a 17500AAIU/g white kidney bean extract. Daily dosage is 371 mg in 3 capsules

Verum T6DIETARY_SUPPLEMENT

Verum T6 is a 34200AAIU/g white kidney bean extract. Daily dosage is 1000 mg in 3 capsules

Verum T7DIETARY_SUPPLEMENT

Verum T4 is a 34200AAIU/g white kidney bean extract. Daily dosage is 512 mg in 3 capsules

Verum T8DIETARY_SUPPLEMENT

Verum T8 is a 34200AAIU/g white kidney bean extract. Daily dosage is 190 mg in 3 capsules.

Verum T9DIETARY_SUPPLEMENT

Verum T9 is a polyphenol mix extract ( olive leaf, and blackcurrant extract). Daily dosage is 1000 mg in 3 capsules

Verum T10DIETARY_SUPPLEMENT

Verum T10 is a polyphenol mix extract ( olive leaf, and blackcurrant extract). Daily dosage is 500 mg in 3 capsules

Verum T11DIETARY_SUPPLEMENT

Verum T11 is a polyphenol mix extract ( olive leaf, pomelo, pomegranate, and blackcurrant extract). Daily dosage is 900 mg in 3 capsules

Verum T12DIETARY_SUPPLEMENT

Verum T12 is a polyphenol mix extract ( olive leaf, pomelo, pomegranate, and blackcurrant extract). Daily dosage is 600 mg in 3 capsules

Verum T13DIETARY_SUPPLEMENT

Verum T13 is a polyphenol mix extract ( olive leaf, pomelo, pomegranate, and/or blackcurrant extract) with white kidney bean extract. Daily dosage is 1000 mg in 3 capsules.

Verum T14DIETARY_SUPPLEMENT

Verum T14 is a polyphenol mix extract ( olive leaf, pomelo, pomegranate, and/or blackcurrant extract) with white kidney bean extract. Daily dosage is 900 mg in 3 capsules.

Verum T15DIETARY_SUPPLEMENT

Verum T15 is a polyphenol mix extract ( olive leaf, pomelo, pomegranate, and/or blackcurrant extract) with white kidney bean extract, Zinc, and, black currant leaf extracts. Daily dosage is 1000 mg in 3 capsules.

Verum T16DIETARY_SUPPLEMENT

Verum T16 is a polyphenol mix extract ( olive leaf, pomelo, pomegranate, and/or blackcurrant extract) with white kidney bean extract, and Zinc. Daily dosage is 1000 mg in 3 capsules.

Verum T17DIETARY_SUPPLEMENT

Verum T17 is a placebo: microcristalline cellulose. Daily dosage is 1000 mg in 3 capsules.