Black Garlic Nutraceuticals and Blood Pressure Control

Universitat de Lleida100 enrolled

Overview

Black garlic contains a series of allyl-sulfur compounds with the ability to modulate nitric oxide synthetase, angiotensin-converting enzyme system, and endothelial activation, which together could help better control blood pressure. The main objective of this study is to evaluate the effect on blood pressure and endothelial health of a daily intake of a black garlic supplement named ABG (registered mark), which has a higher concentration of black garlic bioactive compounds, in people with moderate hypertension.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

TRIPLE

Enrollment

100

Conditions

Hypertension

Interventions

ABG+ Black GarlinDIETARY_SUPPLEMENT

Daily tablet intake during three months

Crystalline CelluloseDIETARY_SUPPLEMENT

Daily tablet intake during three months

Eligibility

Sex: ALLMin age: 18 YearsMax age: 70 Years

Medical Language ↔ Plain English

Inclusion Criteria: \- Clinical hypertension, medically treated with no more than 2 drugs Exclusion Criteria: * Body mass index above 35 kg/m2 * Fasting blood cholesterol levels below 115 mg/dL * Fasting blood glucose levels above 126 mg/dL * Taking anyone of the Angiotensin-converting enzyme inhibitors * Anemia (hemoglobin below 13 g/dL in men and below 12 g/dL in women) * Vitamin or nutraceutical intake in the last 30 days before the study enrollment * Chronic gastrointestinal diseases * Pregnancy and breastfeeding * Garlic allergy * Participation in another study 30 days before the study enrollment

Locations (1)

Hospital Arnau de Vilanova

Lleida, Spain

RECRUITING