The aim of this exploratory pilot study is to assess the feasibility and effectiveness of the adapted T\&E home-based exercise program on the basic functional mobility and executive functions in persons with mild or probable Alzheimer's Disease.
Primary and secondary outcomes will be measured at T0 (one week before the begin of the intervention) and T1, (one week after the eight weeks of the intervention) at home of the participants. Eight home-based physiotherapy sessions will occur in two months, once a week, to activate the preserved implicit memory (PIM). The recommendations are to train three weeks with the same exercise program, three times a week (one time coached by the attributed physiotherapist and two times coached by a natural or family caregiver). After three weeks, the participants can choose if they want to keep the same exercises or change all or some of these, in testing other tasks. Every training session will be planned to last 45 minutes. During each training session, the participant will note on his/her own "Training booklet" each task performed. The "Training booklet" will be used to plane, organize, and remember details for the next training session. Twelve participants will take part at this study.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
TREATMENT
Masking
NONE
Enrollment
12
Eight home-based physiotherapy sessions will occur in two months, once a week, to activate the preserved implicit memory (PIM). The recommendations are to train three weeks with the same exercise program, three times a week (one time coached by the attributed physiotherapist and two times coached by a natural or family caregiver). After three weeks, the participants can choose if they want to keep the same exercises or change all or some of these, in testing other tasks. Every training session will be planned to last 45 minutes. During each training session, the participant will note on his/her own "Training booklet" each task performed. The "Training booklet" will be used to plane, organize, and remember details for the next training session.
CMS Sierre Région
Sierre, Valais, Switzerland
RECRUITINGFunctional mobility
Berg Balance Scale (BBS), scoring ranges from 0 (worse) to 56 (best)
Time frame: 8 weeks
Stand and go
Time Up and Go test (TUG) in seconds
Time frame: 8 weeks
Sit to stand
Five Time Sit to Stand (FTSTS) in seconds
Time frame: 8 weeks
Walking speed
The self-selected and the maximal walking speed (SSWS/MWS) on a 6-meter walk
Time frame: 8 weeks
The Set shifting (Mental flexibility)
Trail Making Test Part-Be in seconds
Time frame: 8 weeks
The updating (Working memory)
Digit span backward task, number of the successful sequences between 0 and 14
Time frame: 8 weeks
The response inhibition
Stroop Color and Word Test (SCWT) Victoria, comparison of the expected score to the participant's score to calculate the Z-score
Time frame: 8 weeks
Feasibility of recruitement
Inclusion of 12 subjects between the 30 of May 2021 ant the 30 of Septembre 2021
Time frame: 4 months
Participation agreement
Fulfilled if 75% of eligible subjects agree to participate and sign the consent
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Time frame: 4 months
Costs
Fulfilled if the cost does not exceed the planed amounts by more than 5%
Time frame: 8 months
Drop out / withdraw
Fulfilled if 75% of the participants take part in the total duration of the study
Time frame: 8 months