Additive Anti-inflammatory Action for Aortopathy & Arteriopathy (Multicenter Cohort Study) III

Nanjing Medical University2,000 enrolled

Overview

Anatomopathological classifications have been well identified in aortic dissection with important therapeutic implications. The authors evaluated the inflammatory response in patients with aortic dissection (AD) and assessed the presence of distinct inflammatory subphenotypes within this disease.

Study Type

OBSERVATIONAL

Enrollment

2,000

Conditions

Aortic Dissection

Interventions

inflammatory responseBIOLOGICAL

laboratory data (leukocyte, neutrophils, monocyte, lymphocytes, platelet, fibrinogen, D-dimer, neutrophils-lymphocyte ratio, platelet-lymphocyte ratio, lymphocyte-monocyte ratio)

Eligibility

Sex: ALLMin age: 18 YearsMax age: 90 Years

Medical Language ↔ Plain English

Inclusion Criteria: * acute type Aortic dissection; Exclusion Criteria: * Iatrogenic aortic dissection OR traumatic aortic dissection * Patients with hematological diseases, infectious diseases, malignant tumors, immune system diseases, or severe liver diseases. * Preoperative use of mechanical ventilation, blood transfusion, renal replacement therapy, extracorporeal membrane oxygenation, or intra-aortic balloon pump during the current admission.

Locations (1)

The first affiliated hospital of nanjing medical university

Nanjing, Jiangsu, China

Outcomes

Primary Outcomes

30-day mortality

any cause death within 30 days of surgery

Time frame: 30 days after surgery

Secondary Outcomes

ICU mortality

any cause death within ICU

Time frame: 7 days after surgery

Data from ClinicalTrials.gov

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