This study is to evaluate the effectiveness of E\>EYE intense regulated pulsed light (IRPL) treatment compared to the current standard of care using a daily warm compress
E-Eye is a medical device that has been specifically designed for treating dry eye syndrome due to meibomian gland dysfunction (MGD). This study is a prospective, single centred, interventional, randomized study assessing the efficacy and safety of E\>EYE in the management of MGD (3 applications on days 0, 15 and 45, with a follow up 1 month later) compared to daily use of a warm compress over a period of 75 days. The study will monitor the change in symptoms and signs of dry eye at each visit.)
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Regulated intense pulsed light therapy
Fabric mask with anti-bacterial coating filled with BodyBeads® heated in a microwave for 30 seconds before application over the eyes for 5 minutes
Market Mall Eye Clinic - Calgary, AB
Calgary, Alberta, Canada
Symptoms of dry eye disease
Change in Ocular Surface Disease Index (OSDI) questionnaire score from baseline to end of trial
Time frame: Change between baseline and day 75
Tear film stability
Change in non-invasive assessed tear film retention time from baseline to end of trial
Time frame: Change between baseline and day 75
Eye redness
Change in ocular redness graded against standardised Efron grading scale (from 0 to 4, where lower is better)
Time frame: Change between baseline and day 75
Meibomian gland patency
Change in the number of glands expressing multiplied by the quality (on a 4 point standardised scale)
Time frame: Change between baseline and day 75
Tear volume
Change in tear meniscus height measured in millimeters
Time frame: Change between baseline and day 75
Lipid layer thickness
Change in white light interferometry pattern graded against the Guillon standardised categories (Open meshwork, closed meshwork, wave pattern, amorphous or colored fringes)
Time frame: Change between baseline and day 75
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.